Vitamina D y Cáncer

[ES]: La vitamina D, o más exactamente su metabolito la 1α,25-dihidroxivitamina D3 (1α,25(OH)2D3, calcitriol), es uno de los principales reguladores de la expresión génica. Modula la transcripción de centenares de genes y la actividad de enzimas y vías de señalización. Sus efectos sobre la proliferación y diferenciación celulares han disparado el interés en la 1α,25(OH)2D3.

[EN]: Vitamin D, particularly its metabolite 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3, calcitriol), is a main regulator of gene expression. 1α,25(OH)2D3 modulates the transcription rate of hundreds of genes and the activity of several enzymes and signalling pathways. A series of novel effects recently described make of 1α,25(OH)2D3 an attractive subject of study.

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Peer Reviewed

Country

Spain

Related Organizations

Spanish National Research Council
Spain

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