Phenylacetyl-Coenzyme A Is the True Inducer of the Phenylacetic Acid Catabolism Pathway in  Pseudomonas putida  U

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2000 English Publisher:American Society for MicrobiologyJournal:Applied and Environmental Microbiology, volume 66, pages 4,575-4,578 (issn: 0099-2240, eissn: 1098-5336,

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Authors: García, Belén; Olivera, Elías R.; Miñambres Rodríguez, Baltasar; Carnicero, David; Muñiz, Carmen; Naharro, Germán; Luengo, José M.;

doi: 10.1128/aem.66.10.4575-4578.2000

pmid: 11010921

pmc: PMC92347

handle: 10261/12206

Phenylacetyl-Coenzyme A Is the True Inducer of the Phenylacetic Acid Catabolism Pathway in Pseudomonas putida U

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Abstract

ABSTRACT Aerobic degradation of phenylacetic acid in Pseudomonas putida U is carried out by a central catabolism pathway (phenylacetyl-coenzyme A [CoA] catabolon core). Induction of this route was analyzed by using different mutants specifically designed for this objective. Our results revealed that the true inducer molecule is phenylacetyl-CoA and not other structurally or catabolically related aromatic compounds.

Keywords

Models, Chemical, Acetyl Coenzyme A, Genes, Bacterial, Pseudomonas putida, Genes, Regulator, Carbon Radioisotopes, Promoter Regions, Genetic, Aerobiosis, Phenylacetates

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