Catalyst-free synthesis of 3-(alkylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids via a three-component condensation

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2014 Spain English Publisher:Elsevier BVJournal:Tetrahedron Letters, volume 55, pages 3,052-3,054 (issn: 0040-4039,

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Authors: Marandi, Ghasem; Saghatforoush, Lotfali; Mendoza-Meroño, Rafael; García-Granda, Santiago;

doi: 10.1016/j.tetlet.2014.03.121

handle: 10261/112982

Catalyst-free synthesis of 3-(alkylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids via a three-component condensation

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Abstract

The synthesis of a number of 3-(alkylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic acids via a facile route involving the reaction between 2-amino-3-pyridinecarboxylic acid, benzaldehyde derivatives, and isonitriles is reported. The structures of the synthesized compounds are proved by X-ray crystallography. © 2014 Elsevier Ltd. All rights reserved.

Financial support was provided by the Research Council of Urmia University, Payame Noor University, the Ministerio de Economía Competitividad de España (MAT2010-15094, Factoría de Cristalización–Consolider Ingenio 2010), and ERDF.

Peer Reviewed

Country

Spain

Related Organizations

Spanish National Research Council
Spain
Payame Noor University
Iran (Islamic Republic of)
University of Oviedo
Spain
Urmia University
Iran (Islamic Republic of)

Keywords

3-(Alkylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids, Arylcarboxaldehydes, Isocyanides, 2-Amino-3-pyridinecarboxylic acid

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