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Los polifenoles, compuestos de origen natural con efectos saludables sobre el sistema cardiovascular

Authors: Quiñones, M.; Miguel, M.; Aleixandre, A.;

Los polifenoles, compuestos de origen natural con efectos saludables sobre el sistema cardiovascular

Abstract

[ES]:En los últimos años numerosos estudios han avalado los efectos beneficiosos de la ingesta de polifenoles sobre la salud, especialmente sobre el sistema cardiovascular. Esto es importante, porque las enfermedades cardiovasculares son la principal causa de muerte en el mundo. Los efectos de los polifenoles son fundamentalmente consecuencia de sus propiedades antioxidantes. Estos compuestos presentan efectos vasodilatadores, son capaces además de mejorar el perfil lipídico y atenúan la oxidación de las lipoproteínas de baja densidad (LDL). Presentan claros efectos antiinflamatorios y estos compuestos son a su vez capaces de modular los procesos de apoptosis en el endotelio vascular. Esta revisión define desde el punto de vista estructural, los distintos grupos de polifenoles que pueden formarse en los vegetales y actualiza los conocimientos sobre su biodisponibilidad. En ella se recopilan asimismo algunos de los estudios recientes que establecen sus propiedades beneficiosas a nivel cardiovascular.

[EN]: In recent years, a number of studies have endorsed the beneficial effects of polyphenols intake on health, especially on the cardiovascular system. This is important since cardiovascular diseases are the main death cause worldwide. The effects of polyphenols are mainly due to their antioxidant properties. These compounds present vasodilating effects, and they can improve the lipid profile and lessen the oxidation of low-density lipoproteins (LDL). They show clear antiinflammatory effects and they can modulate the apoptotic pathways in the vascular endothelium. This review defines from the structural viewpoint the different groups of polyphenols that may occur in vegetables, and updates the knowledge on their bioavailability. Some of the recent studies establishing their beneficial properties at a cardiovascular level are also included.

Este trabajo ha sido financiado por Consolider Ingenio 2010 (CSD-2007-00063 y AGL2008-01740).

Peer reviewed

Keywords

Polifenoles, Health, Enfermedad cardiovascular, Polyphenols, Salud, Cardiovascular disease

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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