
handle: 10234/203066
Objective: to determine the prevalence of hyperuricemia by gender in the Valencian Community, in the population of the IBERICAN-CV sub-study, and how it is associated with other cardiovascular risk factors and with cardiovascular and renal disease. Methodology: this is an epidemiological, multicenter, observational, and crosssectional study that was carried out in primary care clinics in the Valencian Community. Sociodemographic, anthropometric, clinical, and laboratory variables were analyzed in both male and female patients between 18 and 85 years old who met all inclusion criteria and none of the exclusion criteria according to the IBERICAN study. Patients were classified according to gender and whether or not they had hyperuricemia. Results: the study population of the IBERICAN study in the Valencian Community consisted of 770 patients. Of these, 123 patients had hyperuricemia (16%); of which 66 were men (53.66%) and 57 were women (46.34%). Regarding cardiovascular risk factors, a higher prevalence of hypertension, elevated abdominal circumference, sedentary lifestyle, metabolic syndrome, and diabetes mellitus was observed in women. In men, on the other hand, the prevalence was increased in dyslipidemia, tobacco use, obesity and alcohol. Of all these factors, the only significant association was with tobacco use (60.6% of men and 29.8% of women). Cardiovascular and renal risk was increased in men compared to women with hyperuricemia. Conclusions: It has been observed that there is a tendency for patients with hyperuricemia to associate with other cardiovascular risk factors (FRCV), and it is necessary to take a multifactorial approach to reduce them and decrease the socio-sanitary impact.
Objetivo: determinar la prevalencia de la hiperuricemia según género en la población del sub-estudio IBERICAN-CV y cómo se asocia con otros factores de riesgo cardiovascular y con la enfermedad cardiovascular y renal. Metodología: se trata de un estudio epidemiológico, multicéntrico, observacional y transversal, que se llevó a cabo en las consultas de Atención Primaria de la Comunidad Valenciana y que analizó variables sociodemográficas, antropométricas, clínicas y de laboratorio en pacientes de entre 18 y 85 años que cumplían todos los criterios de inclusión y ninguno de exclusión según el estudio IBERICAN. Los pacientes fueron clasificados según el sexo y según si tenían hiperuricemia o no. Resultados: 770 pacientes conformaban la población del estudio IBERICAN en la Comunidad Valenciana. De ellos, 123 pacientes presentan hiperuricemia (16%); 66 hombres (53,66%) y 57 mujeres (46,34%). Respecto a los FRCV, se ha observado que en las mujeres hay una mayor prevalencia de HTA, perímetro abdominal elevado, sedentarismo y síndrome metabólico; en los hombres, por otro lado, la prevalencia estaba aumentada en la dislipemia, el contacto con el tabaco, la obesidad y el alcohol. De todos ellos, la única diferencia significativa fue el contacto con el tabaco. El riesgo cardiovascular y renal estaba aumentado en hombres frente a mujeres con hiperuricemia. Conclusiones: se ha visto que hay una tendencia a que los pacientes con hiperuricemia asocien otros FRCV y se debe actuar de forma multifactorial para reducirlos y disminuir el impacto sociosanitario.
Treball Final de Grau en Medicina. Codi: MD1758. Curs acadèmic: 2022/2023
cardiovascular risk factors, uric acid, Grau en Medicina, Bachelor's Degree in Medicine, gender, Grado en Medicina, ácido úrico, hyperuricemia, hiperuricemia, género, factores de riesgo cardiovascular
cardiovascular risk factors, uric acid, Grau en Medicina, Bachelor's Degree in Medicine, gender, Grado en Medicina, ácido úrico, hyperuricemia, hiperuricemia, género, factores de riesgo cardiovascular
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