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handle: 10234/176677
Introducción: Existe una creciente tendencia a realizar tiroidectomías totales ante múltiples patologías de tiroides, siendo la complicación más frecuente la aparición de hipocalcemia en el postoperatorio. Objetivos: Determinar la incidencia de hipocalcemi a e identificar los factores patológicos y quirúrgicos, que pudieran estar asociados a un mayor riesgo de hipocalcemia en el postoperatorio inmediato de tiroidectomías totales, además de sentar las bases para futuros estudios. Material y métodos: Estudio d e investigación clínica observacional y retrospectivo. Se estudiaron a 94 pacientes tiroidectomizados por el Servicio de Otorrinolaringología del Hospital Universitario de La Plana, entre diciembre de 2014 y enero de 2017. Se definió hipocalcemia subclínic a como valores de calcio corregido inferiores a 8,5 mg/dl e hipocalcemia clínica cuando además se presentaba clínica compatible acompañante. Resultados: Obtuvimos 21 ( 22,3%) casos de hipocalcemia subclínica y 11 (11,7%) casos de hipocalcemia clínica. Los n iveles de PTH - i intraoperatoria bajos se asociaron a una mayor incidencia de hipocalcemia subclínica y clínica. La patología tiroidea hiperfuncionante se relacionó significativamente con niveles de calcio inferiores. Los pacientes con hipocalcemia clínica presentaron signficativamente de media una mayor edad . Conclusiones: La hipocalcemia es una complicación frecuente de las tiroidectomías totales. Niveles bajos de PTH - i intraoperatoria, el hipertiroidismo y una mayor edad son factores asociados a mayor rie sgo de hipocalcemia. No se han encontrado relaciones significativas con otros factores estudiados.
Background: There is an increasing trend of performing total thyroidectomy amongst patients diagnosed with several thyroid diseases, considering hypocalcemia as the most frequent complication during postoperative recovery. Objective : To determine hypocalcemia inciden ce and to identify potential pathological and surgical factors, which may be related to a major risk of hypocalcemia during postoperative immediate period after total thyroidectomy, as well as establishing the foundations for future studies. Methods: Obser vational and retrospective clinical research study. 94 patients that underwent total thyroidectomy were studied by Hospital Universitario de La Plana ENT department, between December 2014 and January 2017. Subclinical hypocalcemia was determined as 8,5 mg/ dl corrected calcium lower levels and clinical hypocalcemia when appearance of compatible symptomatology. Results: Subclinical hypocalcemia was observed in 21 (22,3%) patients and clinical hypocalcemia in 11 (11,7%) patients. Lower intraoperative iPTH lev els were statistically significant associated to a higher subclinical and clinical hypocalcemia. Hyperfunctioning thyroid disease was statistically significant related with lower calcium levels. Patients who suffered from hypocalcemia symptoms showed on av erage an older age. Conclusions: Hypocalcemia is a common total thyroidectomy surgery complication. Intraoperative iPTH, hyperthyroidism and older age are factors associated with a major risk of hypocalcemia. No statistical significant associations with ot her factors studied were identified.
Treball Final de Grau en Medicina. Codi: MD1158. Curs acadèmic: 2017/2018
Hypocalcemia, Grau en Medicina, Bachelor's Degree in Medicine, PTH - i intraoperatoria, Thyroidectomy, Intraoperative iPTH, Grado en Medicina, Hipocalcemia, Hipertiroidismo, Hyperthyroidism, Tiroidectomía
Hypocalcemia, Grau en Medicina, Bachelor's Degree in Medicine, PTH - i intraoperatoria, Thyroidectomy, Intraoperative iPTH, Grado en Medicina, Hipocalcemia, Hipertiroidismo, Hyperthyroidism, Tiroidectomía
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