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Clinical and Biomedical Research
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Article . 2017
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SÍNDROME DA LISE TUMORAL

descriptionPublicationkeyboard_double_arrow_right Article 22 Jul 2017 English Publisher:Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS)Journal:Clinical and Biomedical Research (issn: 2357-9730, Copyright policy )
Authors: Rech, Caroline; Barros, Elvino;

handle: 10183/164261

SÍNDROME DA LISE TUMORAL

Abstract

A síndrome da lise tumoral é caracterizada por complicações metabólicas e desenvolvimento de insuficiência renal aguda, em geral ocorrendo em acientes com neoplasias linfoproliferativas e após o início do tratamento quimioterápico. A hiperuricemia é o distúrbio metabólico mais característico, ocorrendo também hiperfosfatemia, hipocalcemia e hipercalemia. A insuficiência renal é decorrente principalmente da deposição de urato nos túbulos renais. Hidratação vigorosa e administração de alopurinol constituem o manejo principal da síndrome. Identificação precoce e instituição de medidas preventivas são importantes para que se evite o desenvolvimento de dano renal.Unitermos: Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal.

A síndrome da lise tumoral é caracterizada por complicações metabólicas edesenvolvimento de insuficiência renal aguda, em geral ocorrendo em pacientes com neoplasias linfoproliferativas e após o início do tratamento quimioterápico. A hiperuricemia é o distúrbio metabólico mais característico, ocorrendo também hiperfosfatemia, hipocalcemia e hipercalemia. A insuficiência renal é decorrente principalmente da deposição de urato nos túbulos renais. Hidratação vigorosa e administração de alopurinol constituem o manejo principal da síndrome. Identificação precoce e instituição de medidas preventivas são importantes para que se evite o desenvolvimento de dano renal.Unitermos: Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal.

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Keywords

Insuficiência renal, Renal failure, Hematologic diseases, R, Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal, Hyperuricemia, insuficiência renal., Síndrome de lise tumoral, Lise tumoral, hiperuricemia, doenças hematológicas, insuficiência renal., insuficiência renal, Tumor lysis, Medicine, Lise tumoral, hiperuricemia, doenças hematológicas

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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