Flows stress of the steel C45 were predicted on the basis of experimentally obtained flow stress curves, using uniaxial hot compression tests on the plastometer HDS-20, by two completely different types of mathematical models, moreover with comparison to a model comprised in the FEM database of the FORGE software. The tests were carried out within the temperature range from 900 to 1 280 °C, at the strain rate from 0,1 to 100 s-1 and deformations up to 1,0. It follows from the results of flow stress prediction that models designed on the basis of experimental measurements have much better information capability than the generated model implemented into the database of the FORGE software, however, their extrapolation for larger deformations is limited.