Mankind faces a critical challenge to ensure plentiful supply of food,energy, and water (FEW) resources while simultaneously minimizing environmental degradation. FEW systems are interconnected, inter-dependent, and represent a complex web of challenges that span multiple spatial and temporal scales. Addressing these challenges will require adopting holistic systems-based approaches to devise novel solutions and avoid unintended consequences. Achieving sustain-ability and resilience of the FEW nexus will require developing a comprehensive understanding of the domains within which FEW systems are embedded including their interactions with the natural (surrounding ecosystems), engineered (built environment), and social(legal, government, policy) systems ; No Full Text