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G3BP2 valgusünteesi reguleeriv mõju IFITM1 mRNA-le

descriptionPublicationkeyboard_double_arrow_right Thesis 06 Oct 2025 Estonia, Germany Estonian Publisher:Tartu Ülikool
Authors: Lass, Minna-Maria;

handle: 10062/116599

G3BP2 valgusünteesi reguleeriv mõju IFITM1 mRNA-le

Abstract

Bakalaureuse töö eesmärgiks oli hinnata RNA-seonduvate valkude (G3BP2 ja Caprin-1) mõju valgusünteesile kasutades selleks rakuvaba HEK293FT in vitro translatsioonisüsteemi, mis oli kodeeritud reporter IFITM1 mRNA-ga. Tulemustest selgus, et G3BP2 valgul on IFITM1 reportervalgule vähene positiivne mõju valgusünteesile. Sama leiti, et Caprin-1 ja G3BP2 koostoimel on tugev ~ 16 kordne inhibeeriv mõju IFTIM1 translatsioonile. Tulemused viitavad, et G3BP2 ja Caprin-1 mõjutavad IFITM1 mRNA valgusünteesi.,

Countries
Estonia, Germany
Related Organizations
Keywords

IFITM1, G3BP2, bakalaureusetööd, ribosoom, mRNA, RNA-seonduv valk

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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