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Recolector de Ciencia Abierta, RECOLECTA
Bachelor thesis . 2025
License: CC BY NC ND
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Sepsis puerperal por estreptococo pyogenes

Authors: González Mogollón, Andrea Sofía;

Sepsis puerperal por estreptococo pyogenes

Abstract

La sepsis puerperal por Streptococcus pyogenes es una infección invasiva infrecuente pero potencialmente mortal en mujeres en el puerperio. Este trabajo presenta el caso clínico de una paciente previamente sana atendida en el Hospital Universitario de Guadalajara en 2023, quien desarrolló un cuadro de sepsis fulminante 15 días después de una cesárea. La evolución requirió múltiples intervenciones quirúrgicas, incluyendo histerectomía subtotal y anexectomía bilateral, así como un manejo intensivo multidisciplinar, con desenlace favorable. El caso se analiza en el contexto de una revisión bibliográfica que aborda los factores de riesgo, los mecanismos de virulencia del Streptococcus pyogenes, el diagnóstico y las estrategias terapéuticas y preventivas actuales. Se subraya la relevancia del reconocimiento clínico precoz, el inicio urgente de antibioterapia de amplio espectro y el control eficaz del foco infeccioso. Además, se discute la posible transmisión comunitaria, la necesidad de desarrollar escalas de evaluación clínica específicas para el contexto obstétrico y la recomendación emergente de quimioprofilaxis en contactos estrechos. Este trabajo pone de relieve la importancia de una vigilancia activa durante el puerperio y la implementación de protocolos clínicos específicos para mejorar el pronóstico materno en casos de infecciones graves como esta.

Puerperal sepsis caused by Streptococcus pyogenes is a rare but potentially life-threatening invasive infection in postpartum women. This paper presents the clinical case of a previously healthy patient treated at the University Hospital of Guadalajara in 2023, who developed fulminant sepsis 15 days after a cesarean section. The progression required multiple surgical interventions, including subtotal hysterectomy and bilateral adnexectomy, as well as intensive multidisciplinary management, with a favorable outcome. The case is analyzed alongside a literature review that explores risk factors, virulence mechanisms of Streptococcus pyogenes, and current diagnostic, therapeutic, and preventive strategies. The importance of early clinical recognition, prompt administration of broad-spectrum antibiotics, and effective control of the infectious source is emphasized. Additionally, the discussion addresses potential community transmission, the need to develop clinical assessment tools tailored to obstetric settings, and the emerging recommendation of chemoprophylaxis for close contacts. This work highlights the need for active postpartum surveillance and the implementation of specific clinical protocols to improve maternal outcomes in the face of such severe infections.

Grado en Medicina

49 p.

Country
Spain
Related Organizations
Keywords

Streptococcus pyogenes, Medicina, Streptococcal toxic shock syndrome, Puerperium, Infección invasiva, Betahemolítico del grupo A, Sepsis puerperal, Manejo multidisciplinar, Group A Beta-Hemolytic, Síndrome shock tóxico estreptocócico, Multidisciplinary management, Medicine, Puerperal sepsis, Invasive infection, Puerperio

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green