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Proteasas en organismos parásitos

Authors: Giménez Pardo, Consuelo; Armas Serra, Cristina De; Rodríguez Caabeiro, Filomena Crisanta;

Proteasas en organismos parásitos

Abstract

Las proteasas tienen gran importancia en la biología y Fisiología de los seres vivos, por lo que no resulta extraño que estas enzimas hayan sido encontradas en diferentes organismos parásitos implicadas en una gran variedad de procesos propios del parásito, con las procesos de nutrición o de muda y desarrollo así como en las interacciones con el hospedador al invadir sus tejidos digerir sus proteínas o evadir su respuesta inmune (Mc Kerrow 1989) los últimos trabajos apuntan a la posibilidad de utilizar estas enzimas en el control de las parasitosis tanto como fuente de antígenos útiles para la realización de técnicas inmunodiagnósticas como material inmunógeno aplicable en inmunoprofilaxis como blancos de acción de nuevos fármacos antiparasitarios (Song y Chapeil 1993 Williams y Cooms 1995 Armas et al 1995a). Por todo ellos ya que posiblemente el mayor conocimiento de estas enzimas contribuirá a un mejor control de las parasitosis a continuación pasaremos a realizar una revisión bibliográfica de lo realizado al respecto en las últimos años siguiendo una ordenación en cuanto a su estructura química.

Proteases have been implicated in the most important biological and physiological processes of the living organisms although is not rare thing to find them implicated in a variety of activities of the parasite (nutrition or exchysement and growth) as interactions with the host (invading their tissues degrading their proteins or avoiding its immune response) (Mc Kerrow 1989). Recent works propose the possibility of using these enzymes in the control of the parasites, as antigens for making immunodiagnosis or immunoprophylaxis as well as new targets from alternative antiparasitic treatment (Song and Chapeil 1993 Williams and Cooms 1995 Armas et al 1995a). The present revision was made according to the chemical structure of the enzymes.

Facultad de Ciencias Veterinarias

Countries
Spain, Argentina
Keywords

Organismos parásitos, Medicina, Ciencias Veterinarias, Proteasas, Medicine, Parasitología, Biology, Biología y Biomedicina

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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