This paper analyzes Frantz Fanon’s theory of subjectivation in Black Skin, White Mask (1952), through Maria Lugones’ work on The Coloniality of Gender (2007). Assuming the colonial modernity as founded on the co-construction of gender and race, the work of Fanon reveals how those two categories operates simoultaneously in the process of becoming subject. Fanon shows how subjectivation of the colonized has its roots in the desire of lactification, that is in the attempts to become white in order to acced to the being. Analyzing intersubjective relations between the colonized male and the white woman as much as between the colonized female and the white man, lactification is revealed as a gender based dynamics, which confronts the colonized to the impossibility to subjectivate within the normative frameworks of coloniality of gender but rather by calling him into question.