The continuous solid settling during oil sand slurry transportation leads to pipeline blockage. To mitigate this issue, hydraulic flushing process plays a significant role in the oil and gas industries. Water flushing during slurry transportation in pipelines requires a large amount of water to ensure operational efficiencies and system safety. Understanding the flow behavior of slurries and being able to predict how it changes with operating conditions are therefore of practical importance for operators in pipeline design, optimization, and water stewardship during flushing and maintenance. Motivated by the large water demand and down time associated with conventional water flushing, this thesis qualitatively and quantitatively analyzes how slurry composition and carrier-fluid rheology govern mobilization and sustained transport of cohesive deposits inside a lab-scale pipeline; to develop effective, clean strategies for deposit removal while reducing water consumption. Two complementary systems are examined: (i) transport and removal of settled sandbeds under clean water and bubble–laden flows, and (ii) transport and removal of oil–sand (OS) residues using a. water (W), b. non–Newtonian (NN) carriers, and c. micro–bubble & non-Newtonian (MB–NN) fluids.