
El papel de la heparina en pacientes con infarto agudo de miocardio tratados con fibrinoliticos se analizó en dos trabajos (GISSI II, ISIS 3) sin demostrar disminución de la mortalidad . El régimen utlizado es considerado por muchos inadecuado . Varios trabajos demostraron utilidad de la heparina endovenosa luego de fibrinoliticos en el mantenimiento de la permeabilidad arterial ; los mismos no evaluaron mortalidad . La heparina luego de angioplastia parece fisiopatol6gicamente l6gica para evitar la reestenosis pero no existen trabajos que lo avalen . En el tratamiento del trombo mural, 25 .000 UI de heparina subcutanea son útiles ; su use en la prevención del mismo es controvertido
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