Splenic infarction is an uncommon cause of abdominal pain. Diabetes increases the risk of blood vessel occlusion and consequent tissue infarction due to blood vessel abnormalities such as atherosclerosis or thrombosis. Systemic thromboembolism secondary to myocardial infarction is associated with an increased risk of morbidity and mortality. We report the case of a 45-year-old woman with uncontrolled diabetes who presented to the emergency department with the sole complaint of left upper quadrant pain. Upon investigations, it was discovered that she had concomitant splenic and myocardial infarctions. This case demonstrates the significance of thrombotic complications in various organs in patients with uncontrolled diabetes mellitus. Clinicians should have a high suspicion of acute vascular infarction of several organs in poorly controlled diabetic patients with nonspecific symptoms.