A 69-year-old man presented to the ED of our hospital with fever, loss of appetite, malaise, and pyuria and was admitted. He was diagnosed as having Cronobacter sakazakii urinary infection. We instituted treatment with cefmetazole, and he was discharged on hospital day 7. C. sakazakii is a rare infection in adults in Japan. C. sakazakii urinary infection usually occurs as an opportunistic infection in immunocompromised adults or older adults. This patient was not immunocompromised, so Cronobacter spp. should be recognized as potential pathogens in non-diabetic, non-immunocompromised adults.