Classic Kaposi’s sarcoma is one form of Kaposi’s sarcoma. It is usually first seen in the skin of the lower extremities, where it is frequently misdiagnosed as a bruise. As time progresses, the lesions increase in size, number, and color. Early diagnosis is paramount to decrease metastasis to other organ systems such as the lungs, kidneys, and liver. The podiatric physician must take a detailed history, follow the course of the illness, and be aware that definitive diagnosis is made by a skin biopsy. This article provides a case history of Kaposi’s sarcoma and discusses diagnosis and treatment of this disease. (J Am Podiatr Med Assoc 95(6): 586–588, 2005)