Quantum metrology is one of the hot topics in ultra-cold atoms physics. It is now well established that with the help of entanglement, the measurement sensitivity can be greatly improved with respect to the current generation of interferometers that are using classical sources of particles. Recently, Quantum Fisher information plays an important role in this field. In this paper, a brief introduction on Quantum metrology is presented highlighting the role of the Quantum Fisher information. And then a brief review on the recent developments for i) criteria of multi-particle entanglement and its experimental generation; ii) linear and non-linear atomic interferometers; iii) the effective statistical methods for the analysis of the experimental data.