The differential and partial wave scattering cross sections of Ne-H2(D2,T2) collisions have been calculated by close-coupling approximation method using Tang-Toennies potential model at the incident energy of 83.8 meV. The calculated differential cross sections are in good agreement with the experimental data and the partial wave cross sections match well with the published data. With the same method and potential model, the differential cross sections and the partial wave cross sections of Ne-H2(D2,T2) collisions have been derived and analyzed. The rules of the effect of symmetrical isotopic substitution are obtained.