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Évaluation de l’effet de la piézo-corticision et des ostéoperforations sur le mouvement dentaire orthodontique chez le rat

Authors: Sallard, Pauline Léa;

Évaluation de l’effet de la piézo-corticision et des ostéoperforations sur le mouvement dentaire orthodontique chez le rat

Abstract

Objectifs : Comparer l’effet de la piezo-corticision (PC) et de l’ostéoperforation (OP) sur le taux de mouvement dentaire orthodontique (MDO), la morphométrie osseuse et la cicatrisation parodontale chez le rat. Matériel et méthodes : Trente-six rats mâles de type Wistar ont été divisés en 3 groupes (n=12 chacun) : MDO; MDO + PC et MDO + OP. Le MDO a été réalisé à l’aide d’un ressort collé entre la première molaire maxillaire et l’incisive maxillaire droite. La PC a été réalisée au mésio-palatin de la crête alvéolaire de la première molaire supérieure. Deux OPs ont été éffectués en antéro-palatin et mésio-palatin de la première molaire supérieure. Les animaux ont été euthanasiés à 3 et 7 jours suivant la chirurgie. Les échantillons ont été analysés au micro-CT et préparé pour l’analyse histologique. Le MDO, la morphométrie osseuse, ainsi que la cicatrisation parodontale ont été étudiés. Résultats : À 3 jours, le MDO a été significativement plus élevé dans le groupe MDO + PC (219.68 ± 53.6 μm) comparativement au groupe MDO (154.90 ± 35.6 μm ; p=0.051). Aucune différence significative dans le MDO n’a été détectée entre le groupe MDO + OP et le groupe MDO, et entre le groupe MDO + OP et MDO + PC. De plus, le groupe MDO + PC présentait une diminution significativement plus grande des volumes tissulaires (VT; 22.06 ± 2.62 μm) et osseux (VO; 15.55 μm ± 2.65) comparativement au groupe MDO + OP (VT = 23.36 ± 1.40 μm; p=0,001) (VO = 19.03 ± 1.54 μm ; p=0,020). La hauteur de l’os alvéolaire à la furcation était significativement plus réduite dans le groupe MDO + OP (684.2 ± 73.4 μm) comparé au groupe contrôle MDO (559.4 ± 93.5 μm; p= 0.041) et la cicatrisation parodontale était significativement plus avancée dans le groupe MDO + OP comparativement au groupe MDO + PC. À 7 jours, le groupe MDO + PC a démontré une réduction significativement plus élevée du pourcentage de volume osseux (%VO; 67.63 ± 4.49 μm) et une augmentation significativement plus grande du modèle trabéculaire (MT; -29.66 ± 5.22 μm), de la densité de connectivité (DC; 1405.03 ± 519.82 μm) et de la porosité totale ( PT; 32.37 ± 4.49 μm) comparativement au groupe contrôle MDO (%VO= 72.64 ± 2.82 μm ; p=0,051), (MT= -20.97 ± 4.98 μm; p=0,008), (DC= 765.17 ± 165.81 μm; p=0,022), (PT= 27.36 ± 2.82 μm; p=0,051). Conclusion : La PC augmente le taux de MDO à court terme et a plus d’impact sur la morphométrie osseuse. L’OP est associée à une résorption osseuse plus grande à la furcation. La cicatrisation parodontale est retardée avec la PC.

Objectives: To compare the effect of piezo-corticision (PC) and osteoperforation (OP) on the rate of orthodontic tooth movement (OTM), bone morphometry and periodontal healing in a rat model. Material and methods: Thirty-six male Wistar rats were divided into 3 groups (n=12 each): OTM; OTM + PC; OTM + OP. OTM was performed by using a NiTi coil bonded between the maxillary first molar and the maxillary right incisor. PC was performed at the mesio-palatal aspect of the maxillary first molar. Two OPs were performed at the antero-palatal and the mesio-palatal aspects of the maxillary first molar. The animals were euthanized three and seven days after surgery. Samples were analyzed with micro-CT and prepared for histological analysis. The OTM, bone morphometry and periodontal healing were evaluated. Results: At day 3, OTM was significantly increased in the OTM+PC group (219.68 ± 53.6 μm) compared to the OTM only group (154.90 ± 35.6 μm; p=0.051). No significant differences in OTM were detected between OTM+OP and OTM only group, and between OTM+OP and OTM+PC groups. Additionally, the OTM + PC group showed a significantly higher reduction in tissue (TV; 22.06 ± 2.62 μm) and bone volume (BV; 15.55 μm ± 2.65) when compared to the OTM + OP group (TV= 23.36 ± 1.40 μm; p=0,001) (BV= 19.03 ± 1.54 μm; p=0,020). The OTM + OP group showed a significantly higher reduction in bone height in the furcation areas (684.2 ± 73.4 μm) compared to the OTM group (559.4 ± 93.5 μm; p= 0.041) and an earlier periodontal healing compared to the OTM + PC group. At day 7, the OTM + PC group showed a significantly higher reduction in bone volume percentage (BV%; 67.63 ± 4.49 μm) and a significantly higher trabecular pattern factor (TPF; -29.66 ± 5.22 μm), connectivity density (CD; 1405.03 ± 519.82 μm) and total porosity (TP; 32.37 ± 4.49 μm) compared to the OTM group. (BV%= 72.64 ± 2.82 μm; p=0,051), (TPF= -20.97 ± 4.98 μm; p=0,008), (CD= 765.17 ± 165.81 μm; p=0,022), (TP= 27.36 ± 2.82 μm; p=0,051). Conclusion: PC accelerated the amount of OTM in the short term and has more impact on bone morphometry. OP was associated with more bone resorption in the furcation area. The periodontal healing was delayed with PC.

Keywords

Cicatrisation parodontale, Periodontal healing, Mouvement dentaire orthodontique accéléré, Orthodontic tooth movement, Mouvement dentaire orthodontique, Accelerated orthodontic tooth movement, Piézo-corticision, Osteoperforation, Bone remodeling, Remodelage osseux, Piezo-corticision, Ostéoperforation

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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