Ho proved in [A note on the total domination number, Util.Math. 77 (2008) 97--100] that the total domination number of the Cartesian product of any two graphs with no isolated vertices is at least one half of the product of their total domination numbers. We extend a result of Lu and Hou from [Total domination in the Cartesian product of a graph and $K_2$ or $C_n$, Util. Math. 83 (2010) 313--322] by characterizing the pairs of graphs $G$ and $H$ for which $γ_t(G\Box H)=\frac{1}{2}γ_t(G) γ_t(H)\,$, whenever $γ_t(H)=2$. In addition, we present an infinite family of graphs $G_n$ with $γ_t(G_n)=2n$, which asymptotically approximate the equality in $γ_t(G_n\Box G_n)\ge \frac{1}{2}γ_t(G_n)^2$.

11 pages, 3 figures