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Biopolymers and Cell
Article . 2002 . Peer-reviewed
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Biopolymers and Cell
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Наукова електронна бібліотека періодичних видань НАН України (Vernadsky National Library of Ukraine)
Article . 2019
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Isolation and characterization of cold sensitive pex6 mutant of the methylotrophic yeast Hansenula polymorpha

descriptionPublicationkeyboard_double_arrow_right Article 20 Mar 2002Publisher:Institute of Molecular Biology and Genetics (NAS Ukraine)Journal:Biopolymers and Cell, volume 18, pages 131-134 (issn: 0233-7657, eissn: 1993-6842, Copyright policy )
Authors: Nazarko, V. Y.; Pochapinsky, O. D.; Nazarko, T. Y.; Stasyk, O. V.; Sibirny, A. A.;

doi: 10.7124/bc.0005f4

Isolation and characterization of cold sensitive pex6 mutant of the methylotrophic yeast Hansenula polymorpha

Abstract

?????????????? ???????????????????????????????????????? ???????????????????????? ???????????? ???? ?????????????? ???????????? ??????6 ??. polymorpha ?? ???????????????????????? ???????????????????? ????????????????????. ???????????????????????????? ?????????? ?????????????????????????????????????????? ??????6 ???? ???????????????? ?????? ???????????????????????? ?????????????????????? ???????????????????????????? ?? ???????????????? ???????????????????????????? ???????????????????? ????????????????????. ?????????????????????? ?? ???????????????? ?????????????????????? ?????? ?????????????????????????? ???????????????????????? ???? ???????????????? ???????????????????????? ?????????????????????????? ???????? ?????????????????????????????????????????? ???????????? pex6. ???????????????????? ?????????????? ???? ???????????? ???? ???????????????????? ???????????????????? ??. polymorpha.

???????????????? ???????????????????????????? ?????????????????????? ???????????? ???? ?????????? ??????6 ??. polymorpha ?? ?????????????????????? ???????????????????? ????????????????????. ?????????????????????? ?????????? ?????????????????????????????? ??????6 ???? ???????????????? ?????? ?????????????????????? ?????????????????????? ???????????????????? ?? ?????????????????? ???????????????????????? ???????????????????? ????????????????????. ?????????????????? ?? ???????????????? ?????????????????????? ?????? ?????????????????????????? ?????????????????????? ???? ???????????? ???????????????????????? ?????????????????????????? ???????? ?????????????????????????????? ?????????? ??????6. ???????????????? ???????????????? ???? ?????????????? ???? ???????????????????? ???????????????????? ??. polymorpha.

A cold sensitive (cs) suppressor mutant was isolated from the H. polymorpha pex6 strain defective in peroxisome biogenesis. The restored cs pex6 growth on methanol at a permissive temperature was associated with the presence of morphologically normal peroxisomes. The enlarged peroxisomes present at restrictive temperature failed to support methylotrophic growth in the cs pex6 strain. The isolated mutation has no effect on the peroxisome degradation in H. polymorpha.

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    popularity
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    influence
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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