Medication safety protocols include systematic error prevention strategies and risk management systems across healthcare settings. Error prevention mechanisms utilize standardized procedures, technological interventions, and human factors engineering principles to minimize medication-related adverse events. High-alert medication management requires specific safety protocols including standardized concentrations, independent double-checks, and restricted access systems. Risk management programs implement proactive assessment tools, incident reporting systems, and root cause analysis protocols for adverse events. Safety systems incorporate automated alerts, barcode verification, and electronic prescribing with built-in decision support tools. Quality improvement initiatives utilize systematic data collection, outcome measurement, and performance indicators to identify safety gaps and implement targeted interventions. Implementation strategies focus on creating safety culture through staff education, standardized communication protocols, and regular assessment of safety practices