The use of physical, mechanical, chemical, or manual restraints in clinical settings remains a complex medico-ethical issue requiring careful judgment by attending physicians. While restraints may appear to be a convenient means of managing disruptive or unsafe patient behavior, their application must always prioritize patient safety, dignity, and autonomy rather than staff convenience or family pressure. This article outlines the definitions, indications, and limitations of different types of restraints, emphasizing the physician’s responsibility to thoroughly assess underlying medical conditions, medication effects, and potential risks before making a decision. The need to balance potential harm from restraint use against the harm of non-use is highlighted, alongside the importance of reviewing patient history, prior interventions, and multidisciplinary input. Legal implications—particularly the increasing risk of litigation for inappropriate restraint use—underscore the need for judicious, evidence-based decision-making. Ultimately, restraints should be employed only as a last resort after all safer alternatives have been exhausted, ensuring the patient’s well-being and adherence to ethical standards.