The Indian knowledge system of commerce represents a long and rich history of economic theory and practice. In this system, it has a tradition in the manuscripts of the Vedic period in books, for ex. The Arthashastra book of Kautilya has its roots involving a huge diversity of trading methods, economic theories, and managerial practices that have evolved through the millennia, including financial management, market analysis, and regulating trade. The arthashastra provide detailed discussion of trade, taxation, economic policies, and the importance of a controlled economy towards the success of the society. Ancient Indian merchants were popular for their huge trade networks that extended to both Asia and Africa through advanced financial strategies, logistics, and bargaining procedures. A component of modern economic thought proving to be a dynamic union of high-tech innovation and ancient knowledge. It characterized a robust service culture, a fast-growing digital market, and a well-developed business culture of Indian commerce. To address the opportunities and challenges of the present knowledge system, the contemporary Indian business practices are being transformed and adapted at an alarming rate by combining international tendencies with traditional values in historical knowledge. The Indian knowledge system of commerce can be helpful in understanding the evolution of economic practices and their implementation in the contemporary world. By studying the historical effects and activities, companies and other traders will be able to learn some valuable ideas on how to come up with more effective culturally sensitive economic policies and strategies.