This research aimed to identify the psychosocial causes present in the context of remote work within a technology company located in Quito, Ecuador. A quantitative approach was applied, with a non-experimental, cross-sectional, and descriptive design. The sample consisted of 30 intentionally selected employees who performed their duties under remote, hybrid, or occasional on-site modalities. Information was collected using a structured 34-item questionnaire, constructed based on tools previously validated in Latin America: the COPSOQ III, the JCQ, and the ERI. These tools allowed the exploration of different dimensions such as work demands, task control, perceived social support, emotional exhaustion, work–life balance, and the imbalance between effort and rewards. Variables such as work fatigue, task accumulation, emotional exhaustion, and difficulty disconnecting from the digital environment were observed at moderate to high levels, particularly among young women and individuals working more than six hours per day from home. The study demonstrates that extended telework without adequate organizational support can destabilize employees’ emotional well-being. Therefore, it is crucial to establish institutional norms that ensure digital disconnection, sustained emotional support, and recognition of performance. The data obtained provide concrete evidence of an expanding problem in digital workspaces in developing regions.