Solid organ transplant (SOT) recipients receive maintenance immunosuppressive therapy and are at risk of infections and severe infection-related disease. Despite weaker immunological responses to vaccines in SOT recipients compared to controls, this review finds that vaccination has been associated with a lower risk of severe disease, and vaccination before transplantation is recommended in international and Danish guidelines. A national programme for vaccination of SOT candidates has been implemented in Denmark, and vaccination coverage is high for patients participating in the programme.