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Genomic Psychiatry
Article . 2024 . Peer-reviewed
License: CC BY NC ND
Data sources: Crossref
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The association between trace amine-associated receptor 1 (TAAR1) genetic mutations and neuropsychiatric disorders

Authors: Britto Shajan; Tarun Bastiampillai; Pramod C. Nair;

The association between trace amine-associated receptor 1 (TAAR1) genetic mutations and neuropsychiatric disorders

Abstract

Trace amine-associated receptor 1 (TAAR1) is an emerging drug target for the treatment of neuropsychiatric conditions. Several TAAR1-targeted therapeutics are currently in clinical and preclinical development. Emerging studies highlight links between TAAR1 single-nucleotide variants/polymorphisms and neuropsychiatric disorders. An improved understanding of TAAR1 genetic variants and their functional impact will inform the potential role of the TAAR1 system in the pathophysiology of neuropsychiatric conditions and for better therapeutic dosing. This viewpoint examines clinical and molecular studies involving TAAR1 genetic variants and their association with neuropsychiatric disorders.

  • BIP!
    Impact byBIP!
    citations
    The total number of citations received by all articles of the researcher of interest.
    2
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Top 10%
Average
Average
gold