Additional file 7: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer
NIH| Pleiotropic functions of FOXC2 in EMT, stem cells and breast cancer progression
Vijay, Geraldine; Zhao, Na; Hollander, Petra; Toneff, Mike; Joseph, Robiya; Pietila, Mika; Taube, Joseph; +14 Authors
Vijay, Geraldine; Zhao, Na; Hollander, Petra; Toneff, Mike; Joseph, Robiya; Pietila, Mika; Taube, Joseph; Sarkar, Tapasree; Ramirez-Pena, Esmeralda; Werden, Steven; Shariati, Maryam; Gao, Ruli; Sobieski, Mary; Stephan, Clifford; Sphyris, Nathalie; Miura, Noayuki; Davies, Peter; Chang, Jeffrey; Soundararajan, Rama; Rosen, Jeffrey; Mani, Sendurai;
Additional file 7: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer
Figure S5. HMLE-vector and HMLE-Snail cells were treated with a dose range of the tested inhibitors, and viability was assessed by MTT assay. Of the drugs that were shortlisted from the screen, BIO was one of the drugs that could selectively inhibit HMLE-Snail cells with mesenchymal phenotype more efficiently as compared to HMLE-vector cells with epithelial phenotype. (PDF 133â kb)
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