This thesis explores the integration of genomic data into vascular surgery, focusing on how genetic insights can enhance understanding, diagnosis, and treatment of vascular diseases. It reviews the genetic basis of conditions such as atherosclerosis, aneurysms, and venous insufficiency, and examines the impact of advanced sequencing technologies on these areas. The thesis discusses personalized medicine approaches, including how genetic profiles can guide tailored surgical interventions. Additionally, it addresses the challenges and future directions in applying genomics to clinical practice, with case studies illustrating practical applications and research findings. This work aims to provide a comprehensive overview of how genomics is reshaping the field of vascular surgery, highlighting both current advancements and potential future developments.