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Article . 2021
Full-Text: https://figshare.com/articles/journal_contribution/Additional_file_7_of_Prediction_and_mechanistic_analysis_of_drug-induced_liver_injury_DILI_based_on_chemical_structure/13605398
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Other literature type . 2021
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Additional file 7 of Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

descriptionPublicationkeyboard_double_arrow_right Other literature type , Article 01 Jan 2021Publisher:figshareFunded by:UKRI | Moving the Adverse Outcom...
Authors: Liu, Anika; Walter, Moritz; Wright, Peter; Bartosik, Aleksandra; Dolciami, Daniela; Elbasir, Abdurrahman; Hongbin Yang; +1 Authors

doi: 10.6084/m9.figshare.13605398.v1 , 10.6084/m9.figshare.13605398

Additional file 7 of Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

Abstract

Additional file 7: TableS2. Proteins with high feature importance in RF and SVM, and links to DILI. The 19 proteins with the highest feature importance in RF or SVM models are shown. The feature importance is shown in bold if the protein ranked among the top 19 in the respective model. Many proteins identified possess known functions in liver drug metabolism and cell stress. Those proteins with plausible involvement in DILI are indicated in italics.

Keywords

Pharmacology, Mechanistic models, Chemical Sciences not elsewhere classified, Protein target, Information Systems not elsewhere classified, Structural alerts, Biochemistry, Cancer, Biological Sciences not elsewhere classified, Drug-induced liver injury (DILI)

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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