Powered by OpenAIRE graph
Found an issue? Give us feedback
addClaim

ИЗУЧЕНИЕ РАСПРЕДЕЛЕНИЯ ЧАСТОТЫ ВСТРЕЧАЕМОСТИ ПОЛИМОРФИЗМА PRO12ALA ГЕНА PPARG У УЗБЕКСКИХ СПОРТСМЕНОВ

A STUDY OF THE FREQUENCY DISTRIBUTION OF THE PPARG GENE PRO12ALA POLYMORPHISM IN UZBEK ATHLETES

ИЗУЧЕНИЕ РАСПРЕДЕЛЕНИЯ ЧАСТОТЫ ВСТРЕЧАЕМОСТИ ПОЛИМОРФИЗМА PRO12ALA ГЕНА PPARG У УЗБЕКСКИХ СПОРТСМЕНОВ

Abstract

Solving specific problems that are of great importance, both for sports in general and for each person personally, is associated with understanding the influence of the mechanism of heredity on health and improving a person’s athletic performance. The purpose of our work was to study the frequency of occurrence of genotypes of the Pro12Ala polymorphism of the PPARG gene in Uzbek athletes. The results of our study showed that the frequency distribution of the ProAla alleles of the PPARG gene polymorphism revealed that the frequency of occurrence of the Pro allele in the group of athletes involved in boxing (3.3%, p = 0.006) and football (7.9%, p = 0.000006) significantly exceeds the frequency of occurrence of this allele in the control group (12.4%). Thus, the above statistical analysis showed a statistically significant increase in the frequency of alleles, as well as genotypes, in football players and boxers compared to the control group.

Решение конкретных задач, имеющие огромное значение как для спорта в целом, так и для каждого человека лично, связано с пониманием влияния механизма наследственности на здоровье и повышение спортивных результатов человека. Целью нашей работы явилось исследование частоты встречаемости генотипов полиморфизма Pro12Ala гена PPARG у узбекских спортсменов. Результаты нашего исследования показали, что распределения частот аллелей ProAla полиморфизма гена PPARG выявил, что частота встречаемости аллеля Pro в группе спортсменов, занимающихся боксом (3,3%, р=0,006) и футболом (7,9%, р=0,000006) достоверно превышает частоту встречаемости данного аллеля в контрольной группе (12,4%). Таким образом, вышеприведенный статистический анализ показал статистически достоверное повышение частоты встречаемости аллелей, а также генотипов у футболистов и боксеров по сравнению с контрольной группой.

Cifra. Биологические науки, Выпуск 2 (2) 2024

Keywords

PPARG gene, генетическая предрасположенность к физическим качествам, Pro12Аla полиморфизм, gene polymorphism, genetic predisposition to physical qualities, Pro12Ala polymorphism, DNA, полиморфизм генов, ДНК, ген PPARG

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Related to Research communities
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!