The ability of microorganisms, especially bacteria become resistant, has been widely discussed in various publications, and plants are one source to search for new drugs that each day has become more necessary. This work aimed to evaluate different ways of preparing extracts of Brassica oleracea var. capitata and test them fronts strain of Staphylococcus aureus using the test on solid medium by diffusion in agar and in liquid medium in the ELISA plate. Tests revealed that extracts obtained by solvent extraction and decoction hydroalcoholic acid have greater appeal to the search for new drugs with activity against S. aureus, and the latter fractions obtained by liquidliquid partition relating to solvents ethyl acetate, dichloromethane and hydroalcoholic remaining fraction showed more efficient. As for the solid medium, there was a lack of antibacterial activity of hydroalcoholic extract. However, a strong antibacterial activity was observed when analyzed in the same extracts in liquid medium. Ethanolic extracts with concentrations of 50 and 70% showed better results when evaluated for 8 h of incubation. Different results were observed when the period was bent where the concentrations became more expressive of the 70 and 80%. The results demonstrate that the species is a potential source of antibacterial agents. However, the choice of solvent, the extraction method and the bacterial growth medium should be considered. The data shown here motivates further studies for the isolation and identification of the active principles responsible for the antibacterial activity that can be used in the pharmaceutical industry, because of the large number of resistance to existing antibacterial drugs. Key-words: Anti-Bacterial Agents, Plants Medicinal, Medicine Traditional, Phytotherapy, Brassica.