Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ African Journal of B...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
African Journal of Biotechnology
Article . 2010 . Peer-reviewed
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
African Journal of Biotechnology
Article
License: CC BY
Data sources: UnpayWall
https://dx.doi.org/10.60692/76...
Other literature type . 2010
Data sources: Datacite
https://dx.doi.org/10.60692/sk...
Other literature type . 2010
Data sources: Datacite
versions View all 4 versions
addClaim

Biological activities of Peganum harmala leaves

English
Authors: Hayet Edziri; Maha Mastouri; Mata Matieu; Zine Mighri; Laura T. Gutman; Mahjoub Aouni;

Biological activities of Peganum harmala leaves

Abstract

Les extraits d'acétate d'éthyle, de chloroforme, de butanol et de méthanol des feuilles de Peganum harmala ont été testés pour leurs activités antibactériennes, antioxydantes et antivirales. L'activité antibactérienne a été évaluée par la détermination de la concentration minimale inhibitrice (CMI) en utilisant la technique du milieu solide. L'activité antivirale a été évaluée contre la souche de cytomégalovirus humain (HCMV) AD-169 (ATCC Ref. VR 538) et le virus Coxsackie B de type 3 (CoxB-3) en utilisant la méthode de diagnostic de culture « shell-vial ». L'activité antioxydante a été évaluée en utilisant la méthode au thiocyanate d'ammonium. Parmi les extraits testés, les extraits de méthanol et de chloroforme ont montré une activité antibactérienne plus élevée contre les bactéries gram-positives que les bactéries gram-négatives. L'extrait de méthanol a démontré l'activité antioxydante la plus élevée et une bonne activité antivirale contre le HCMV.

Se analizaron los extractos de acetato de etilo, cloroformo, butanol y metanol de las hojas de Peganum harmala para detectar actividades antibacterianas, antioxidantes y antivirales. La actividad antibacteriana se evaluó mediante la determinación de la concentración inhibitoria mínima (MIC) utilizando la técnica del medio sólido. La actividad antiviral se evaluó contra la cepa AD-169 del citomegalovirus humano (HCMV) (ATCC Ref. VR 538) y virus Coxsackie B tipo 3 (CoxB-3) utilizando el método de diagnóstico de cultivo de 'vial de cáscara'. La actividad antioxidante se evaluó utilizando el método de tiocianato de amonio. Entre los extractos probados, los extractos de metanol y cloroformo mostraron una mayor actividad antibacteriana contra bacterias grampositivas que gramnegativas. El extracto de metanol demostró la mayor actividad antioxidante y una buena actividad antiviral contra HCMV.

Ethyl acetate, chloroform, butanol and methanol extracts of the leaves of Peganum harmala were tested for antibacterial, antioxidant and antiviral activities.The antibacterial activity was evaluated by the determination of minimum inhibitory concentration (MIC) using the solid medium technique.The antiviral activity was evaluated against human cytomegalovirus (HCMV) strain AD-169 (ATCC Ref. VR 538) and Coxsackie B virus type 3 (CoxB-3) using diagnostic method 'shell-vial' culture.The antioxidant activity was evaluated using ammonium thiocyanate method.Among tested extracts, methanol and chloroform extracts displayed a higher antibacterial activity against gram-positive than gram-negative bacteria.The methanol extract demonstrated the highest antioxidant activity and good antiviral activity against HCMV.

تم اختبار مستخلصات أسيتات الإيثيل والكلوروفورم والبيوتانول والميثانول من أوراق بيغانوم هارمالا بحثًا عن الأنشطة المضادة للبكتيريا ومضادات الأكسدة والفيروسات. تم تقييم النشاط المضاد للبكتيريا من خلال تحديد الحد الأدنى من التركيز المثبط (MIC) باستخدام تقنية الوسط الصلب. تم تقييم النشاط المضاد للفيروسات ضد سلالة الفيروس المضخم للخلايا البشرية AD -169 (مرجع ATCC. VR 538) وفيروس كوكساكي ب من النوع 3 (CoxB -3) باستخدام طريقة تشخيصية "قشرة فيال". تم تقييم النشاط المضاد للأكسدة باستخدام طريقة ثيوسيانات الأمونيوم. من بين المستخلصات المختبرة، أظهرت مستخلصات الميثانول والكلوروفورم نشاطًا مضادًا للبكتيريا أعلى ضد البكتيريا إيجابية الجرام من البكتيريا سالبة الجرام. أظهر مستخلص الميثانول أعلى نشاط مضاد للأكسدة ونشاطًا جيدًا مضادًا للفيروسات ضد HCMV.

Keywords

Pharmacology, Toxicology and Pharmaceutics, Organic chemistry, Antioxidant Properties, Toxicology, Antimicrobial Activity, Biochemistry, Agricultural and Biological Sciences, Biochemistry, Genetics and Molecular Biology, Genetics, Ammonium thiocyanate, Molecular Biology, Biology, Chromatography, Bacteria, Peganum harmala, antimicrobial, antiviral, antioxidant, activities, leaves, Life Sciences, Antioxidant Activity, Traditional medicine, Antimicrobial Properties of Essential Oils in Foods, Chemistry, Role of Quinones in Toxicology and Pharmacology, FOS: Biological sciences, Medicine, Antimicrobial, Chloroform, Antibacterial activity, Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids, Antioxidant, Food Science, Peganum harmala

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    18
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
18
Top 10%
Top 10%
Average
gold