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African Journal of Biotechnology
Article . 2008 . Peer-reviewed
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African Journal of Biotechnology
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Stimulation of taxane production in suspension cultures of Taxus yunnanensis by oligogalacturonides

English
Authors: Ting Guo Yu; Wen Wang Jian;

Stimulation of taxane production in suspension cultures of Taxus yunnanensis by oligogalacturonides

Abstract

When Taxus yunnanensis cells of 12-day-old cultures were exposed to oligogalacturonide (OGA) at 20-80µg ml-1 for 3 days, it was found that paclitaxel and 10-deacetyl baccatin III (10-DAB III) content peaked at 23 and 24 µg g-1 dry wt, respectively. OGA treatment increased taxane release percentage(extracellular release ratio) from 10 to 90%. The maximum production of paclitaxel and 10-DAB III in cultures elicited with OGA at 40 µg ml-1 was demonstrated to be 0.5 and 1.0 mg l-1, a 3.6 and 3.4-fold that of the control. This is the first report on the stimulation of taxoid production by OGA

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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