For the process of creating new medications, stability is very essential. Any pharmaceutical product that wants to be approved or accepted must first undergo stability tests, which ensure that the product's quality, safety, and efficacy will not change over its shelf life. By providing comprehensive information about drug stability, the principle of drug degradation, force degradation studies, stability studies and their classification, factors affecting drug stability, the mechanism of drug degradation, stability testing, and various methods to increase drug stability, this article will close the knowledge gap on the most crucial topic for researchers or developers who are developing a formulation. Since the various sources discussed above in this article address issues related to drug stability, they will also influence individuals who are science or research oriented to develop formulations by offering comprehensive knowledge on this particular topic