There was a growing interest in the development of CSCL (Computer Supported Collaborative Learning) environments over the last decade. Despite the plethora of tools available, they ignore the cultural differences between learners. In fact, especially, in the case of distant learning, these environments may bring together learners from different socio-cultural backgrounds that have acquired different socio-cultural values and behaviors and developed different needs, points of view and learning styles. Thus, CSCL environments need to be socio-culturally adapted to each learner’s culture. The main goal of this paper is to emphasize the need of socio-cultural aware collaborative learning, to present our proposed ontology-driven adaptation approach to meet this need, its operationalization and its experimental validation. Results and limits are discussed at the end of the paper.