The ZnOrgBAT project aims to develop next-generation zinc-based energy-storage systems by combining highly cyclable Zn anodes with high-capacity organic cathodes. Since the performance and durability of these batteries are critically influenced by the behaviour of the zinc anode, a fundamental understanding of its degradation mechanisms is essential for guiding electrode and cell design. This contribution first provides an overview of the most common challenges associated with zinc anodes, together with the corresponding mitigation strategies typically adopted. It then presents an integrated summary of recently published studies by the co-authors, covering a range of different anode architectures and additive chemistry. Across these works, X-ray microtomography (XμCT) and microradiography (XμR) played a central role in elucidating key morphochemical processes, such as dead-metal formation, redistribution of active phases, gas-induced mechanical degradation, and in correlating these structural dynamics with electrochemical behaviour.