Clinical significance of Ag-NORs-staining in multiple myeloma.
Copyright policy ) Masahiko OHATA; Shinobu NAKAMURA; Youko OKABE;
Clinical significance of Ag-NORs-staining in multiple myeloma.
本研究では多発性骨髄腫multiple myeloma: MMの骨髄標本におけるAg-NORs染色を試みた.MMのAg-NORs染色で得られたドットは, 数・大きさ・染色パターンに多様性があった.われわれは, ドットの染色パターンにより独自のscoringsystemを考案し, 臨床の場で応用されている病期分類, 形態分類と対比して検討を行った.このscoringsystemは, 病期分類に比し形態分i類とよく相関していた.また, totalscore≧300群は生存期間が有意に短く予後不良であった.totalscore≥300群は, ゆっくりした経過をとり化学療法なしに観察できる症例と思われた.経過を観察し得た症例では, 病勢を反映してAg-NORsの染色パターンが変化した.Ag-NORsは, MMの予後因子として, また治療選択の上からも重要な指標として臨床的意義は大きく, 本scoring systemは実用的なものであると考えられた.
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
selected citations
Citations provided by BIP!
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 0
Average
Average
Average
bronze
Fields of Science