Today, one of the state-of-the-art technologies that have shown its importance towards data integration and analysis is the linked open data (LOD) systems or applications. LOD constitute of machine-readable resources or mechanisms that are useful in describing data properties. However, one of the issues with the existing systems or data models is the need for not just representing the derived information (data) in formats that can be easily understood by humans, but also creating systems that are able to process the information that they contain or support. Technically, the main mechanisms for developing the data or information processing systems are the aspects of aggregating or computing the metadata descriptions for the various process elements. This is due to the fact that there has been more than ever an increasing need for a more generalized and standard definition of data (or information) to create systems capable of providing understandable formats for the different data types and sources. To this effect, this chapter proposes a semantic-based linked open data framework (SBLODF) that integrates the different elements (entities) within information systems or models with semantics (metadata descriptions) to produce explicit and implicit information based on users’ search or queries. In essence, this work introduces a machine-readable and machine-understandable system that proves to be useful for encoding knowledge about different process domains, as well as provides the discovered information (knowledge) at a more conceptual level.