The topic of this chapter is the antibacterial activity of Mentha against several pathogenic bacteria. Some aromatics plants are recently been studied for their antibacterial properties, such as citrus essential oils, Armoracia rusticana etc., showing inhibition against bacteria, fungi and yeasts. The chapter highlights the antibacterial and characteristics of Mentha piperita (peppermint) and other Mentha sp., that are very used daily as folk remedies and in industry too. Mentha act as acts as counterirritant and analgesic with the ability to reduce pain and improve blood flow to the affected area. For these reasons mint essential oils are very studied in fact antibacterial activities against both Gram-negative and Gram positive ones and can be a useful help as substitute of some antibiotics and combat the antimicrobial bacterial resistance