Takotsubo cardiomyopathy Takotsubo cardiomyopathy occurs worldwide. The condition is thought to be responsible for 2% of all acute coronary syndromes’ cases presenting to hospitals. Although it has generally been considered a self-limiting disease, spontaneously resolving over the course of days to weeks, a subset of patients may present with symptoms arising from its complications, e.g., heart failure, pulmonary oedema, stroke, cardiogenic shock, or cardiac arrest. It occurs more commonly in postmenopausal women.