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InTech
Part of book or chapter of book . 2023
Data sources: InTech
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
https://doi.org/10.5772/intech...
Part of book or chapter of book . 2023 . Peer-reviewed
License: CC BY
Data sources: Crossref
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Orally Disintegrating Tablets

Authors: Fikadu, Ejeta,;

Orally Disintegrating Tablets

Abstract

Research and development costs for a single new pharmaceutical that is introduced to the market are estimated to cost between $1 billion and $2 billion. Due to the high cost of development and the need to quickly access various technologies, it is more cost-effective (clinically and financially) to enhance current pharmaceuticals for potency, selectivity, drug metabolism, and dosing convenience before they reach the market. Orally dissolving tablets have been developed as a result. Pharmaceutical companies have created oral disintegrating tablets that dissolve or disintegrate in the mouth within a few seconds of being placed there in order to maximize the safety and efficacy of the medicine molecule. Because patients with weak physiological (patients with mental illnesses) and physical capacities can easily administer it to geriatrics, children, and patients with these conditions (patients suffering from dysphagia), as well as traveling patients who may not have easy access to water and where swallowing conventional solid oral-dosage forms presents difficulties, it has grown in popularity among a wide population. These tablets can be prepared in many ways like direct compression, freeze drying, sublimation, molding, and spray drying by using single or combinations of superdisintegrants or subliming agents.

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
Green
hybrid
Related to Research communities