Cutaneous candidiasis is a multipicture infection of the skin, generally caused by yeast like fungus c.albicans or other species of genus candida such as candida parapsilosis, candida tropicalis, candida glabrata but these species are unusual, secondary to skin diseases. Candida is flora of gut microbiota, rather than skin, although it is present on skin at some instances. Certain factor of candida species such as ability to evade host defense by biofilm formation, filamentous form and presence of tissue damaging enzyme phospholipase are attributed to pathogenicity. Cutaneous candida infection may occur in patient HIV/AIDS, cancer receiving chemotherapy, antibiotics, steroids therapy and in organ transplantation. Vesicles, pustules, maceration and fissuring are common symptoms on perineum, axilla and interriginous areas. Systemic and topical therapies are common treatment with different drugs. Single drug therapy as combination of anti-fungal, antibacterial and topical corticosteroid has marvelous results. Nystatin, Clotrimaziole and miconazole are efficiently reviewed topical drugs with 73–100% cure.