Abstract Cancer of uterine cervix and ovaries are the common female genital organ cancers. Cervical cancer is preventable primarily by vaccination and secondarily by treating pre-cancer lesions as the surrogate markers by programmatic screening methods. There is programmatic gap in ovarian cancer care due to lack of screening tool and specific surrogate markers. Ovarian cancer may progress without symptom for longtime because of intra-abdominal location of organ. Therefore, the disease may be revealed incidentally on casual imaging study only. Predicting modality will be clinical, imaging study, biochemical, biomolecular or their combinations for different tools. Its intervention will also be contextual depending on availability and affordability of resources. Thus, the comprehensive clinical practice guideline or diagnostic model or approach should address every level of socioeconomic and geographical sector for the graded care facility.