The construction industry has one of the highest high fatality and injury rates globally. Building Information Modelling (BIM) as an enabling technology can significantly eliminate and mitigate risks and improve work health and safety (WHS) management. Adoption is inconsistent, although various guidelines and legislation have been developed to reduce incidents and injuries in the workplace. Our literature review indicates that the UK, Singapore, Hong Kong, US, Germany, Spain and Finland public and private sectors are relatively advanced in the development of BIM technology. The US has been a significant contributor through its collaborative links with the UK, Australia, South Korea, Germany and Spain. In contrast, the integration of BIM and WHS management is less advanced. Australia, the site of this study has lacked research that evaluates WHS management in a BIM-environment. To increase BIM-WHS management integration across the industry, a government, industry and academic collaboration in Australia was undertaken, resulting in the development of comprehensive evidence-based guidelines comprising four key components: (1) Developing Information Requirements, (2) BIM for WHS Best Practice, (3) Procurement, Tendering and Supply Chain Monitoring and (4) Developing Project Information Requirements. The comprehensive iterative collaborative process that underpinned the development and distribution of the guidelines is described.