This chapter on breast reduction provides a comprehensive overview of the surgical and non-surgical procedures aimed at reducing the size and reshaping the breasts. It delves into the goals of breast reduction surgery, including alleviating physical discomfort, improving body proportions, and enhancing overall quality of life. This chapter discusses the surgical planning involved, considering factors such as desired breast size, nipple placement, and patient anatomy. Various breast reduction techniques are discussed, including the traditional wise pattern and vertical scar methods. The chapter also discusses the use of various pedicles versus free nipple grafting. Lastly, this chapter discusses the importance of monitoring and following patient outcomes post-surgery, assessing factors such as healing, scarring, and patient satisfaction. Through a comprehensive examination of these components, this chapter serves as a valuable resource for both patients considering breast reduction and healthcare professionals involved in their care.