The most important cause of diseases that many do not know is increased acidity in the body! The body must remain moderate between acidic and alkaline in the normal ratio or lean slightly toward alkalinity, but now the human body has become more acidic! Due to the frequent consumption of sugars, meat, cheese, milk derivatives, pastries, canned food, preservatives, chemicals, etc., fungi and algae are microscopic living organisms rich in nutrients and compounds with therapeutic properties. With the increase in awareness of health and the search for sustainable food sources, interest has increased in its role in nutrition, spices, and treatment. In this chapter, we will discuss these concepts and the importance of the red or reishi mushrooms, Ganoderma lucidium, and the algae, Spirulina platensis.