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InTech
Part of book or chapter of book . 2016
Data sources: InTech
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
https://www.intechopen.com/cit...
Part of book or chapter of book
License: CC BY
Data sources: UnpayWall
https://doi.org/10.5772/61968...
Part of book or chapter of book . 2016 . Peer-reviewed
Data sources: Crossref
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Temperature-Dependent Regulation of Bacterial Gene Expression by RNA Thermometers

Authors: Yahan Wei; Erin R. Murphy;

Temperature-Dependent Regulation of Bacterial Gene Expression by RNA Thermometers

Abstract

RNA thermometers (RNATs) are cis-encoded regulatory elements that modulate transla‐ tional efficiently in response to environmental temperature. Since their initial discovery, numerous RNATs have been identified and characterized, with the majority of currently known RNATs present in a wide variety of bacterial species. RNATs repress translation at relatively low temperatures by physically preventing binding of the ribosome to the regulated transcript by incorporating the Shine-Dalgarno sequences (and/or start codon) into an inhibitory structure. As the environmental temperature increases, the inhibitory structure within the RNAT is destabilized and the repression of translation initiation is gradually relieved. With the development of identification techniques, the rate at which RNATs are identified, and the understanding of the molecular mechanisms governing their regulator function, has grown exponentially. With the ever-increasing number of characterized RNATs, broad families of these regulators have now been identified. It has also become abundantly clear that RNATs influence several essential physiological proc‐ esses. This chapter aims to summarize the current knowledge of bacterial RNATs, with special emphasis placed on the molecular mechanisms underlying RNAT function, exper‐ imental techniques used to identify and characterize RNATs, families of bacterial RNATs, as well as biological processes controlled by RNATs, and future directions of the field.

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    12
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
12
Top 10%
Average
Average
Green
hybrid